When taken orally, the absorption is high. Evenly distributed in the body, it enters the smooth muscle cells. Maksamalnoy blood concentration reaches over 2 h. Contact with blood plasma proteins – 80 – 90%. The half-life of 7-12 hours. Andriol dosage actively metabolized in the liver, kidneys displayed mainly, to a lesser extent in the bile.It does not cross the blood-brain barrier.
Indications for use:
When the pain and spasms (spastic nature) arising under the following conditions:
- spasm of smooth muscles of internal organs (renal colic, biliary colic, intestinal colic)
- dyskinesia when zhelchevshodyaschih tract and gall bladder for hyperkinetic type, with holetsestit, postcholecystectomy syndrome;
- spastic constipation, spastic colitis, proctitis, tenesmus;
- pilorospazme, gastroduodenitis, gastric ulcer and 12 duodenal ulcer (in the acute phase in the complex therapy – to relieve pain syndrome, spastic nature);
- spasm of peripheral, coronary arteries, as well as spasm of cerebral arteries, accompanied by headaches;
- to reduce the excitability of the uterus during pregnancy (miscarriage menacing, threatening preterm labor); spasm of the uterus shed during labor, prolonged throat opening, after-pains.
For the prevention of spasm:
- during some andriol dosage instrumental studies holetsistografii.
Hypersensitivity expressed renal and hepatic failure, chronic heart failure, atrioventricular block II and III degree, cardiogenic shock, hypotension.
Spazmonet tablets contain lactose, therefore patients with congenital galactose intolerance, lactase deficiency or glucose-galactose malabsorption should not take the drug. With Precautions: children under 6 years of age, expressed atherosclerosis of the coronary arteries, angle-closure glaucoma, prostatic hyperplasia.
Pregnancy and lactation:
The appointment of the drug during pregnancy and lactation andriol dosage is not contraindicated. Be wary appointed in pregnancy (I trimester) and lactation.
Nausea, dizziness, palpitations, feeling hot, sweating, blood pressure, allergic skin reactions.
Symptoms violates atrioventricular conduction in large doses, reduces the excitability of the heart muscle can cause heart failure and paralysis of the respiratory center.
In the treatment of gastric ulcer and 12 duodenal ulcer drug is used in combination with other anti-ulcer agents.
Effects on ability to andriol dosage drive a car and operate machinery:
During the period of the drug should refrain from driving motor vehicles and activities potentially hazardous activities that require concentration and speed of psychomotor reactions. steroid purchase online steroid suppliers uk buy steroids online